Bradbury PJ, Zhang Z, Kroon DE, Casstevens TM, Ramdoss Y, Buckler ES. (2007) TASSEL: Software for association mapping of complex traits in diverse samples. Bioinformatics 23:2633-2635.
TASSEL is a software package to evaluate traits associations, evolutionary patterns, and linkage disequilibrium. Strengths of this software:
1. It provides a number of new and powerful statistical approaches to association mapping such as a General Linear Model (GLM) and Mixed Linear Model (MLM). MLM is an implementation of the technique which our recently published Nature Genetics paper - Unified Mixed-Model Method for Association Mapping - which reduces Type I error in association mapping with complex pedigrees, families, founding effects and population structure.
2. Ability to handle a wide range of indels (insertion & deletions). Most software package ignore this type of polymorphism, however, in some species (like maize) this is the most common type of polymorphism.